NPO Guidelines in Pediatric Surgery


The practice of "nil per os" (NPO), or nothing by mouth, for children undergoing surgery has been a subject of intense scrutiny and evolution over the years. Various studies and guidelines highlight the balance between minimizing the risk of pulmonary aspiration during anesthesia and reducing the adverse effects of prolonged fasting on children?s metabolic and psychological well-being.

Historically, the NPO protocol has been rigid, often enforcing a midnight fast for all patients scheduled for surgery. This practice, aimed at preventing aspiration, has faced criticism for its negative impact on children. Prolonged fasting can lead to dehydration, hypoglycemia, and behavioral issues like irritability and anxiety. Studies show that the current international guidelines allow more flexibility, advocating for fasting durations of 2 hours for clear liquids, 4 hours for breast milk, and 6 hours for solids. However, these guidelines are frequently exceeded in practice due to scheduling inefficiencies and miscommunication.

One of the major challenges identified is parental compliance with fasting instructions. Research indicates that less than 10% of parents fully adhere to the prescribed NPO times, with most either under-fasting or over-fasting their children. The reasons for non-compliance include inadequate understanding of instructions, fear of surgical delays or cancellations, and the difficulty of denying food or drinks to a distressed child. Miscommunication between healthcare providers and parents further exacerbates the issue, as conflicting or unclear instructions lead to confusion. Studies recommend clearer communication strategies, such as providing separate written instructions for solids and liquids and ensuring consistency in messaging.

The metabolic implications of prolonged fasting are particularly concerning for pediatric patients, as their smaller glycogen reserves make them more susceptible to hypoglycemia. This metabolic stress not only affects their energy levels but also impairs their ability to cope with the stress of surgery, potentially delaying recovery. Research highlights the benefits of shorter fasting periods, noting that children allowed to consume clear liquids up to 2 hours before surgery exhibit better hydration, reduced irritability, and lower gastric pH levels without increasing the risk of aspiration.

Recent quality improvement initiatives have shown promise in addressing the shortcomings of current NPO practices. For instance, allowing children to drink clear liquids up to 1 hour before surgery has been shown to significantly reduce fasting times and improve overall patient comfort. Such liberalized fasting guidelines align with modern evidence suggesting that aspiration risk does not increase with shorter fasting durations. These changes have been endorsed by leading anesthesia societies in Europe and Canada, emphasizing the importance of minimizing disruption to normal physiological states preoperatively.

Despite these advancements, the implementation of more liberal NPO guidelines faces resistance. Anesthesiologists and surgeons often express concerns about flexibility in scheduling and the potential for last-minute changes in surgery times. This conservatism results in a default return to the midnight fasting rule in many institutions, particularly for inpatients or cases with higher perceived aspiration risks. To counter this, some hospitals have developed task forces to standardize and enforce updated guidelines, incorporating strategies like using arrival times instead of surgery times to calculate fasting periods and encouraging the administration of clear liquids closer to the surgery.

Compliance with updated NPO guidelines also varies significantly across healthcare settings. Data show that prolonged fasting is more common in settings with less robust quality improvement frameworks or where the operational culture is resistant to change. For example, effective fasting times for clear liquids can extend beyond seven hours, even when shorter durations are recommended. Educational initiatives targeting healthcare providers and parents are critical in bridging this gap, ensuring both groups understand the rationale and safety of revised fasting protocols.

The adverse effects of prolonged fasting extend beyond the physiological to the psychological, with many children experiencing heightened anxiety and behavioral challenges due to hunger and thirst. These factors contribute to a less favorable surgical experience, both for the patient and their family. Addressing these issues requires a multifaceted approach, including better preoperative education, consistent adherence to evidence-based guidelines, and ongoing monitoring and adjustment of fasting practices based on patient outcomes.

In conclusion, while significant strides have been made in revising and liberalizing NPO guidelines for children, the practical application of these recommendations remains inconsistent. Barriers such as communication lapses, entrenched practices, and operational constraints continue to impede progress. Moving forward, greater emphasis on quality improvement initiatives, clearer communication strategies, and more flexible approaches to fasting durations are essential to enhance compliance and improve the overall surgical experience for pediatric patients. These changes must be supported by ongoing research and a willingness among healthcare providers to adopt evidence-based practices, ensuring that children receive care that is both safe and compassionate.

References:
1- Brunet-Wood K, Simons M, Evasiuk A, Mazurak V, Dicken B, Ridley D, Larsen B: Surgical fasting guidelines in children: Are we putting them into practice? J Pediatr Surg. 51(8):1298-302, 2016
2- Beazley B, Bulka CM, Landsman IS, Ehrenfeld JM: Demographic Predictors of NPO Violations in Elective Pediatric Surgery. J Perianesth Nurs. 31(1):36-40, 2016
3- Kafrouni H, Ojaimi RE: Preoperative Fasting Guidelines in Children: Should They Be Revised? Case Rep Anesthesiol. 2018:8278603, 2018
4- Friedrich S, Meybohm P, Kranke P: Nulla Per Os (NPO) guidelines: time to revisit? Curr Opin Anaesthesiol. 33(6):740-745, 2020
5- Singla K, Bala I, Jain D, Bharti N, Samujh R: Parents' perception and factors affecting compliance with preoperative fasting instructions in children undergoing day care surgery: A prospective observational study. Indian J Anaesth. 64(3):210-215, 2020
6- Schmidt AR, Fehr J, Man J, D'Souza G, Wang E, Claure R, Mendoza J: Pre-operative fasting times for clear liquids at a tertiary children's hospital; what can be improved? Anesth Pain Med (Seoul). 16(3):266-272, 2021


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